Lipid polymorphism and membrane properties

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Phases with cubic symmetry have been observed in lipid-water systems since the early days of lipid polymorphism, at a time when it seemed all too natural to presume without closer inspection that phases with such high symmetry should consist of spherical micelles of type I or II, orderly packed in a cubic lattice ( Luzzati et al., 1960; Luzzati and Reiss-Husson, 1966).