Magical Tome

The outer archives are busy
During their development in the bone marrow, B cell precursors undergo sequential recombination-activating gene (RAG)-mediated rearrangements of D to J and V to DJ elements of the immunoglobulin (Ig) heavy-chain variable region (VH) and V to J elements of the Ig light-chain variable region (VL) (Tonegawa, 1983).
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